
Pain Release™
Herbal tincture for everyday aches
Herbal tincture · 2 fl oz (60 ml)
Formulated by the practitioners of the Zoi Well clinic since 2015.
What it does- Supports comfort, circulation and healthy joints and muscles
- Relaxes muscle tension and occasional cramping
- Supports healthy blood flow, even in the smallest vessels
- Supports a healthy inflammatory response
- Supports bone, sinew and connective tissue
- Gentle enough to take daily
Free shipping on orders of $65 or more and on every subscription; $6.95 ground shipping under that. In stock, ships from Buda, TX within 1–3 business days. US only. In Europe or the UK? Our partner Sarah Walker Wellness carries Zoi and ships across Europe.
3 of the 16 herbs in Pain Release™.
Every herb is tested for heavy metals, bacteria, fungus and pesticides. See the full ingredient list and the Traditional Chinese Medicine view of each.
Corydalis rootYan Hu Suo · Corydalis yanhusuoYan Hu Suo moves the Blood and Qi: the herb Chinese medicine reaches for first when something aches.
Spatholobus stemJi Xue Teng · Spatholobus suberectusJi Xue Teng moves and nourishes the Blood, easing stiffness and aching limbs.
Dan shen, red sage rootDan Shen · Salvia miltiorrhizaRed sage root, used in Chinese medicine to move the Blood and calm the Heart.
What it’s good for
Pain Release is a formula for everyday aches that can be taken daily. It supports circulation and bone health rather than masking a signal, so it suits the back, knees and muscles that have been holding since morning. Take it steadily for ongoing support, or more often for a flare.
How to take it
Standard adult dose: two droppers full (1.5 ml) three times a day, under the tongue or in water. Use the standard dose three times a day for everyday comfort. Use the standard dose 30 minutes before physical activity for preventive support. For a flare, use 2–3 droppers full as needed, not to exceed five droppers full at a time. For long-standing aches, use it consistently for 4–6 weeks to allow its full effect. Pairs with Longevity for a healthy inflammatory response and with Kidney Meridian for the low back and knees.
Questions
Is it safe with my medication?
Herbal supplements can interact with prescribed medication. Zoi formulas are gentle, but blood thinners, blood-sugar medication, thyroid medication and immune-suppressing drugs are the ones to check. If you are pregnant, breastfeeding or taking any prescription, talk with your physician or practitioner before beginning a formula, and tell them the herbs on the label.
How long before I notice a difference?
Zoi formulas are fast-acting: many people feel a change within 15 minutes of a dose, and most notice a difference within days. The building formulas, the Organ Meridians, Longevity and Resilience, show their best results after four to six weeks of steady use. Consistency matters more than the size of the dose.
Pain Release is a formula for the back, knees, neck and muscles that have been holding since morning. Sixteen herbs work together through several connected pathways rather than one. Cramp bark and Bai Shao relax tight muscle. Dang Gui, Chuan Xiong and Dan Shen support circulation. Xu Duan and Sang Ji Sheng support bone and sinew. It supports comfort, circulation and healthy joints and muscles, and it can be taken daily.
Ingredients and the Traditional Chinese Medicine view
Zoi Medicinals tinctures are alcohol and vegetable glycerin extracts of non-toxic herbs. All herbs used in the manufacturing of Zoi Medicinals products have been tested for heavy metals, bacteria, fungus, and pesticides.
- Yan Hu Suo (Corydalis Root, Corydalis yanhusuo) is warm and enters the LIV and HT meridians; invigorates Blood, promotes movement of Qi, and supports comfort. The foremost herb for comfort in the Chinese pharmacopeia, used for over 1,100 years.
- Ji Xue Teng (Spatholobus Stem, Spatholobus suberectus) is warm and enters the LIV, SP, and HT meridians; invigorates and tonifies Blood, relaxes sinews, opens the channels and collaterals, and supports comfort where there is Blood stagnation or deficiency.
- Dan Shen (Salvia Root, Salvia miltiorrhiza) is slightly cold and enters the HT and LIV meridians; invigorates Blood and dispels stasis, clears Heat, cools the Blood, nourishes Blood, and calms the Spirit.
- Qin Jiao (Gentiana Root, Gentiana macrophylla) is cool and enters the ST, LIV, and GB meridians; dispels Wind-Dampness, relaxes sinews, and supports comfort. Uniquely moistening among Wind-Damp herbs; used for both hot-type and cold-type Bi syndrome.
- Du Huo (Pubescent Angelica Root, Angelica pubescens) is slightly warm and enters the KI and UB meridians; dispels Wind-Cold-Dampness, opens channels and collaterals, and supports comfort, particularly in the lower back and lower extremities.
- Dang Gui (Chinese Angelica Root, Angelica sinensis) is warm and enters the LIV, HT, and SP meridians; tonifies and invigorates Blood, regulates menstruation, disperses Cold, and supports comfort.
- Bai Shao (White Peony Root, Paeonia lactiflora) is cool and enters the LIV and SP meridians; nourishes Blood, softens and calms the Liver, preserves Yin, supports comfort, and relaxes muscle cramping and spasms.
- Mo Yao (Myrrh Resin, Commiphora myrrha) is neutral and enters the HT, LIV, and SP meridians; invigorates Blood, dispels stasis, reduces swelling, generates flesh, and supports comfort. A primary resin in TCM for Blood stagnation.
- Chuan Niu Xi (Cyathula Root, Cyathula officinalis) is neutral and enters the LIV and KI meridians; invigorates Blood and dispels stasis, strengthens sinews and bones, and guides the formula's action downward to the lower body.
- Willow Bark (Salix alba) enters the LIV and KI meridians; clears Heat, supports comfort and a healthy inflammatory response, and stops bleeding. The botanical source of salicin, used for centuries in western herbal medicine.
- Chuan Xiong (Szechuan Lovage Root, Ligusticum chuanxiong) is warm and enters the LIV, GB, and PC meridians; invigorates Blood, promotes movement of Qi, expels Wind, and supports comfort. Carries the formula's effects upward, balancing Chuan Niu Xi's downward direction.
- Fang Feng (Siler Root, Saposhnikovia divaricata) is slightly warm and enters the UB, LIV, and SP meridians; releases the Exterior, expels Wind-Dampness, and supports comfort. Acts as a "wind screen" to protect the channels from external pathogenic invasion.
- Crampbark (Viburnum opulus) enters the LIV and SP meridians; relaxes smooth and skeletal muscle, eases cramping and spasms, and supports comfort. A specific western antispasmodic with a long history of use for neuromuscular tension.
- Gui Zhi (Cinnamon Twig, Cinnamomum cassia) is warm and enters the HT, LU, and UB meridians; warms the channels, opens the collaterals, promotes Blood circulation, and assists the Yang. Directs the formula's action to the extremities and upper body.
- Xu Duan (Dipsacus Root, Dipsacus asper) is slightly warm and enters the LIV and KI meridians; tonifies the Liver and Kidneys, strengthens sinews and bones, reconnects sinews and bones, and promotes healing of injured tissues.
- Sang Ji Sheng (Taxillus Twig, Taxillus chinensis) is neutral and enters the LIV and KI meridians; tonifies the Liver and Kidneys, strengthens sinews and bones, expels Wind-Dampness, and nourishes Blood.
About alcohol
Zoi Medicinals formulas contain 18.25% alcohol. Alcohol has been used in herbal tinctures for centuries. It extracts active ingredients that are not water-soluble, such as essential oils, alkaloids and resins. It enables the tincture to be fast-acting, potent, shelf-stable for long periods of time, and enables their "grab and go” properties (easily portable, ready to take, no refrigeration required). Zoi Medicinals tinctures use organic ethyl alcohol that is USP certified. It is the same alcohol found in vanilla extract (used for cooking), other tinctures, and liquid homeopathic remedies. The dose is very small and can be diluted into water or other drink making the final alcohol content less than 0.5%, which is similar or less than, the amount of alcohol in a cup of kombucha.
How to use
- Use the standard dose three times a day for everyday comfort.
- Use the standard dose 30 minutes before physical activity for preventive support.
- For a flare, use 2–3 droppers full as needed, not to exceed five droppers full at a time.
- For long-standing aches, use it consistently for 4–6 weeks to allow its full effect.
Dosage
Liquid formulas are rapidly absorbed by the body and should be taken by mouth. Hold under the tongue a few moments prior to swallowing; or take in a small amount of water or juice. If alcohol content is a concern, a standard dose (1.5 ml) in one cup of water dilutes the alcohol content to less than 0.5%, or formula can be added to hot tea (alcohol will evaporate) and drink once cooled.
The standard, adult dose is two droppers full (1.5 ml) three times a day, stepping down to twice a day for maintenance, or as directed by your health care professional. One full compression of the dropper bulb is a dropper full, about 0.75 ml (the dropper may not appear “full”).
- Standard adult dose — 2 droppers full (1.5 ml), three times a day; twice a day for maintenance.
- Standard child dose (30–100 lb) — 1 dropper full, three times a day.
- If sensitive to herbs and supplements, start with 1 dropper full, three times a day.
Cautions
- Do not use if pregnant or breastfeeding, unless directed by your health care practitioner. This formula contains multiple blood-invigorating herbs.
- Use caution if taking anticoagulant or antiplatelet medications (warfarin, aspirin, clopidogrel), as multiple ingredients promote blood circulation and may potentiate their effects.
- Use caution if allergic to aspirin or salicylates, as this formula contains willow bark and crampbark.
- With minor stomach upset, take with food.
- Not to exceed five droppers full at a time.
- Discontinue use if any new symptoms appear, including symptoms of allergic reaction.
- If experiencing minor headache or other discomfort, reduce the dosage to ⅓ of starting dose. Gradually increase the dosage each day until you reach the desired dosage.
- Every body is different; as the formula alters internal processes, your best dosage may change (always stay within the recommended dosage range).
Biomedical details and references are in the full fact sheet. This product is not intended to diagnose, treat, cure or prevent any disease.


